Occupational Asthma Treatment,Occupational Asthma,Occupational Asthma Diagnosis,Occupational Asthma Causes,Occupational Asthma symptoms

Occupational Asthma Treatment, Symptoms, Diagnosis, & Prognosis

Asthma Types

Occupational Asthma Treatment, Symptoms, Diagnosis, & Prognosis: It is caused by exposure to asthmatic substances in the occupational environment. Typical occupational asthma manifests as coughing, wheezing, chest tightness, or symptoms such as rhinitis and conjunctivitis during or after work. The occurrence of symptoms is closely related to the working environment. Occupational Asthma Treatment, Symptoms, Diagnosis, & Prognosis. Its incidence is also related to the nature of asthma, such as the long-term exposure to asthmatic isocyanate workers, the incidence of occupational asthma is 5% to 10%, in the detergent industry and long-term contact with proteolytic enzymes Among the workers, the incidence rate is 50% or even higher. With the development of industry, the incidence of occupational asthma in China is also increasing year by year. Specific bronchial provocation tests are the most diagnostic method for diagnosing occupational asthma and screening for occupational asthma. Avoiding contact with allergens is the most important measure for treating occupational asthma. Occupational Asthma Treatment, Symptoms, Diagnosis, & Prognosis.

What We Will Learn:

1: Occupational Asthma Causes

2: Symptoms of Occupational Asthma

3: Occupational Asthma Test

4: Occupational Asthma Diagnosis

5: Occupational Asthma Treatment

6: Occupational Asthma Prognosis

1: Occupational Asthma Causes:

1: Internal cause

It has been found that occupational asthma practitioners engaged in high molecular weight allergen-related industries generally have atopic physiques, and studies have been shown to be associated with the patient’s genetics. These people are more prone to asthma after exposure to asthma, allergens easily enter the body, B lymphocyte reactivity is abnormally increased, and specific IgE is produced after contact with allergens to form a sensitized state when occupational allergens are again It is easy to induce allergic reactions and asthma attacks in the body.

2: Causes

The causes of occupational asthma are divided into high molecular weight biological substances and low molecular weight chemicals, most of which are occupational asthma and a few are irritants. There are more than 250 types of asthmatic factors that have been recorded so far, and many suspicious factors remain to be determined.
The causes of occupational asthma are divided into high molecular weight biological substances and low molecular weight chemicals, most of which are occupational asthma and a few are irritants. There are more than 250 types of asthmatic factors that have been recorded so far, and many suspicious factors remain to be determined.
  • I: Plant dust, flour, soybeans, castor beans, coffee beans, tea leaves, tobacco leaves, vegetable gum, cottonseed, linseed, etc.
  • II: Animal body composition and its excretion laboratory animals, birds, eggs, milk, crabs, shrimps, etc.
  • III: Insect family dust mites, gluten, poultry, silkworms, crickets, bees, etc.
  • IV: Enzyme papain, succinyl lase, trypsin, pepsin, trypsin, fungal amylase, and the like.
  • V: Vegetable gum arabic gum, tragacanth gum, carrageenan, and the like.
  • VI: Isocyanates such as toluene diisocyanate (TDI), methylene diphenyl diisocyanate, hexamethylene diisocyanate, and the like.
  • VII Phthalic anhydrides such as phthalic anhydride, trial lithic anhydride, and triphenyl hexa carbon hydride.
  • VIII Drugs such as penicillin, cephalosporin, spiramycin, tetracycline, piperazine citrate, and the like.
  • IX: Wood dust such as mahogany, cedar, maple, oak, and other wood dust.
  • X: Metals such as platinum, nickel, chromium, cobalt, and the like.
XI Other rosins, formaldehyde, ethylenediamine, ammonium thioglycolate, and the like.
Among them, 1 to 5 are high molecular weight biological substances, and 6 to 11 are low molecular weight compounds. At present, the scope of occupational asthma in China is classified into isocyanates, phthalic anhydrides, amines, platinum complex salts, and sisal.
Occupational asthma can be divided into high molecular weight allergen prototypes and low molecular weight allergen prototypes based on differences in asthmatic factors. According to the pathophysiological mechanism, it can be divided into immune-mediated and non-immune-mediated. Immune-mediated patients have an incubation period, which can be divided into two types: IgE-mediated and non-IgE-mediated. The former is mostly induced by high molecular weight allergens and a few low molecular weight allergens. The latter is only found in Low molecular weight allergen-induced occupational asthma. Non-immune-mediated patients have no incubation period for asthma attacks, and the inflammation of the airway can be caused by the direct stimulation of asthma, and can also be induced by the pharmacological action of asthma to stimulate mast cells, smooth muscle cells or nerve fibers.

2: Symptoms of Occupational Asthma

Typical occupational asthma manifests as coughing, wheezing, chest tightness, or symptoms such as rhinitis and conjunctivitis during or after work. The occurrence of symptoms is closely related to the working environment. The rapid-onset asthmatic response induced by high-molecular-weight occupational asthma is manifested in the presence of asthmatic symptoms when the patient enters the work environment. The symptoms are relieved quickly after leaving the scene, and the contact working environment – asthma attack – separation from the working environment – asthma relief – Contact recurrence characteristics. Occupational asthma induced by low molecular weight asthma is a delayed asthmatic reaction. The symptoms of asthma appear sometime after work, so they are easily overlooked or misdiagnosed.

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3: Occupational Asthma Test:

1: Laboratory examination
Specific IgE testing uses common allergens and specific allergen complexes for skin testing to determine whether a patient has the atopic physique and to help determine whether a patient is sensitive to a specific occupational allergen. IgE antibodies against occupational allergens in patients’ serum can be detected by radioactive allergen adsorption test (RAST) or ELISA. These two methods are more sensitive but less specific.
2: Other auxiliary inspections
  • I: Pulmonary function The indicators used for occupational asthma include PEF and FEV1 (forced expiratory volume in one second). Continuous observation of PEF has a certain significance in the diagnosis of occupational asthma.
  • II: Non-specific bronchial provocation test The continuous non-specific bronchial provocation test with formyl choline or histamine can confirm whether the patient has airway hyperresponsiveness and assist in judging the relationship between changes in airway responsiveness and the working environment.
  • III: Specific bronchial provocation test is a gold indicator for the diagnosis of occupational asthma. The test has certain risks and requires a professional operation and emergency measures.

4: Occupational Asthma Diagnosis

There is currently no uniform standard for the diagnosis of occupational asthma. First, you must establish a diagnosis of asthma, and then further determine the relationship between asthma attacks and occupations, and find out asthma. There are mainly the following points. ‘Occupational Asthma Treatment, Symptoms, Diagnosis, & Prognosis’
1: Clear diagnosis
According to the diagnostic criteria of asthma, the diagnosis can be confirmed based on medical history, clinical manifestations, signs at the onset of symptoms, and laboratory tests such as pulmonary function tests.
2: Identify the relationship between asthma and occupation
Careful inquiry about the patient’s current medical history and past history can generally lead to clues. Asthma can be suspected if the patient has no previous history of asthma, has asthma after starting new work or work with new materials, and has asthma in the work environment; colleagues who work in the same environment have similar episodes. Cases; asthma attacks are related to the work environment, and symptoms are relieved after work or transfer.
3: Looking for asthma
It can help to find occupational asthmatic factors through specific laboratory tests such as specific skin tests, serological tests, and specific bronchial provocation tests. Currently, specific bronchial provocation tests are considered to be the most diagnostic method for screening occupational asthma.

5: Occupational Asthma Treatment

The purpose of treatment is to quickly control symptoms, restore normal airway responsiveness, and prevent irreversible changes in the airway. Once an occupational asthma is diagnosed, the patient should be removed from the susceptibility environment. Avoiding contact with allergens is the most important measure for the treatment of occupational asthma. Repeated exposure to a sensitizing environment can exacerbate airway inflammation. Inhaled corticosteroids can effectively prevent airway inflammation. The use time can be as long as half a year. The sooner the airway inflammation is eliminated, the less likely it is that irreversible changes will occur. Sometimes combined with hormones and bronchodilators to relieve symptoms. Inhalation of cromolyn prevents certain allergen-induced allergic reactions.

6: Occupational Asthma Prognosis

The mortality rate of asthma is about 2/100,000, and the mortality rate is related to the patient’s socioeconomic status, medical security conditions and past medical history. “Occupational Asthma Treatment, Symptoms, Diagnosis, & Prognosis”. What we Recommend to Occupational Asthma patients is you should Talk to a Doctor As Soon As Possible.

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